Suppression of high lipid diet induced atherosclerosis by sarpogrelate
This study was undertaken to test that SP suppresses the development of atherosclerosis due to high cholesterol diet (HCD) by decreasing blood viscosity and oxidative stress. For this purpose, 29 rabbits were divided into four groups: control group (normal diet); normal diet group with SP at the dose of 5 mg/kg/day; HCD group fed 1% cholesterol; and HCD group with SP at the dose of 5 mg/kg/day. After 90 days of the experiment, blood samples were collected and the animals were sacrificed; the thoracic aorta was stained by the Oil...
Published By: MedWorm/Stress - Wednesday, 22 February