Protective Effect of Recombinant Hirudin Variant III against Galactose-Mediated Rat Lens Epithelial Cell Damage.

Conclusions: The protective effects of rHV3 may be due to effective recovery of the antioxidative defense system, resulting in antiapoptosis. In addition, rHV3 may be able to inhibit apoptosis of lens epithelial cells through the mitochondrial pathways of apoptosis by regulating Bcl-2 and Bax expression. PMID: 22335805 [PubMed - in process] (Source: Current Eye Research)...