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Impaired Neuroendocrine and Immune Response to Acute Stress in Medication-Naive Patients With a First Episode of Psychosis

Little is known about how the biological stress response systems—the autonomic nervous system (ANS), the hypothalamic-pituitary-adrenal (HPA) axis, and the immune system—function during psychosis. Results of studies on the effect of stress on the immune and autonomic system in patients with schizophrenia are inconsistent. The present study investigates whether the stress response is impaired in medication-naive patients with a first episode of psychosis. Ten male patients with a first episode of psychosis and 15 controls were exposed to the stress of public speaking. Parameters of the ANS (heart rate and...

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Published By: MedWorm/Stress - Wednesday, 22 February

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