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Genetic modulation of plasma NPY stress response is suppressed in substance abuse: Association with clinical outcomes

Conclusion: These preliminary findings are the first to document chronic drug abuse influences on NPY diplotype expression where NPY diplotype modulation of stress-related plasma NPY, heart rate and anxiety responses was absent in the substance abuse sample. The finding that lower stress-related NPY is predictive of greater relapse severity provides support for therapeutic development of neuropeptide Y targets in the treatment of substance use disorders. (Source: Psychoneuroendocrinology)...

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Published By: MedWorm/Stress - Wednesday, 22 February

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