Executive dysfunction in euthymic bipolar disorder patients and its association with plasma biomarkers
Abstract: Background: Despite the old Kraepelinean concept that bipolar disorder (BD) does not evolve with cognitive decline, the presence of cognitive impairment, especially executive dysfunction has been recognized in BD patients. Brain-derived neurotrophic factor (BDNF) and pro-inflammatory molecules are important contributors to the pathophysiology of BD, and imbalance in peripheral levels of these molecules may be implicated in the cognitive decline observed in BD patients. We aimed to investigate the executive performance of BD type I euthymic patients and its relation with the plasma levels of BDNF, TNF-α and its...
Published By: MedWorm/EatingDisorder - Wednesday, 22 February
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Vote! The epidemiology of hypernatraemia in hospitalised children in Lothian: a 10-year study showing differences between dehydration, osmoregulatory dysfunction and salt poisoning MedWorm/EatingDisorder (Yesterday) - Conclusions Hypernatraemia after 2 weeks of age is uncommon, and on admission is usually associated...