Endothelial-derived neuregulin is an important mediator of ischaemia-induced angiogenesis and arteriogenesis

Conclusion Endothelial production of NRG is required for angiogenesis and arteriogenesis induced by ischaemic injury. Furthermore, exogenous administration of rNRG can enhance this process, suggesting a potential role for NRG in vascular disease. (Source: Cardiovascular Research)...