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Comparison of Low and High Dose Cosyntropin Stimulation Tests in the Diagnosis of Adrenal Insufficiency in Septic Shock Patients
In this study, we compared both tests in septic shock patients taking a special interest in the population with intermediary baseline cortisol. Prospective noninterventional study included 74 septic shock patients. After measurement of baseline cortisol all patients received 1 μg of cosyntropin i. v. and 4 h later 249 μg of cosyntropin. We compared the cortisol increase after each test and its relation to mortality and vasopressor therapy. There was a moderate correlation in response to low and high dose cosyntropin, rs=0.55. This correlation in patients with baseline cortisol between 10–34 μg/dl is, rs=0.67. The...
Published By: MedWorm/Stress - Wednesday, 22 February
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